This research used the new U.S. state Energy Policy Simulators (EPS) to identify the top five state policies for reducing greenhouse gas (GHG) emissions across states with very different emissions profiles including Louisiana, Michigan, Minnesota, New Mexico, Pennsylvania, and Wisconsin. The EPS modeling finds just five policies—clean electricity standards; zero-emission vehicle standards; clean building equipment standards; industrial efficiency and emissions standards; and standards for methane detection, capture, and destruction—can dramatically cut state GHG emissions, create anywhere from 13,000 to 118,000 jobs, grow the economy 1 to 3 percent, and prevent between 90 and 3,800 asthma attacks annually in 2030.